AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |
Back to Blog
Compare two amino acid sequences8/2/2023 The above suggests that we must consider both identities and similarities between the amino acids in calculating the alignment score. On the other hand, substituting V with R may have a dramatic negative effect and destabilize or denature a protein. The same applies, e.g., to K and R substitution, since both these residues are usually located on the surface and primarily interact with solvent or with the acidic side chains of E or D. For example, L and V will be equally tolerated within a protein's hydrophobic core, assuming enough space is available for the slightly larger side chain of leucine to be accommodated. For this reason, this type of conservation is called similarity, and it depends on the demand for the conservation of structure and function. Many replaced residues will be chemically equivalent to the "original" ones. The higher this percentage, the closer the compared sequences will be in terms of their evolutionary origin.Įven though many amino acids in a protein sequence can be invariant, depending on the evolutionary distance between the proteins, there will always be a substantial number of residue substitutions caused by mutations. Using this number, we can count the percentage of identical residues – called the percentage of sequence identity. The most straightforward score to assess how closely related two sequences are can be based on the number of identical amino acids that align against each other. This suggests that the alignment score is essential, and its calculation needs careful consideration. The alignment software sorts the generated alignments according to a calculated score, with the output being the one with the highest score. First, however, we must remember that an alignment generated by software will represent only one of many different possible alignments. There are many ways to align two protein sequences against each other.
0 Comments
Read More
Back to Blog
Torrent in firefox versions8/2/2023 When selecting none of the options in the Calamares bootloader field, the installation won’t crash anymore.A fix for slower machines during the installation process causing a time-out during the build of the kernel images (intrams).In general, it is superior to mkinitcpio in it’s ability to autodetect needed modules and for most use cases will work without any further configuration. We now also install the system with Dracut, a highly modular tool for generating initramfs images, instead of mkinitcpio by default. This will enhance the experience to install a system to your liking from step one. Reorganized and cleaned up the netinstall packagesĪs you can read on top of the list, we now offer the options to install the system without a bootloader, systemd boot or GRUB.Budgie: is set to Qogir Icons and arc GTK theme and uses Nemo instead of Nautilus (to have even theming possible, Nautilus is not able to get theming from Budgie).GNOME: uses Console and Gnome-text-editor instead of now legacy gedit and gnome-terminal, Wallpaper follows night and day theme same for Console (it is set to dark only by upstream default).Cinnamon: Replaced adwaita icons with Qogir.KDE/Plasma: Replaced the discover icon with a Konsole icon.Default wallpaper/background is now set by settings packages instead of welcome.Grub submenu feature is now enabled by default (only default entry is visible extra entries are inside a submenu).You can now choose to create a new EFI partition instead of re-using the existing one when using “Replace partition” or “Install alongside“.Added an entry for Windows when using grub or systemd-boot and Windows is installed.Added a choice of bootloaders as well as the ability to not install a bootloader ( systemd-boot is default selected).The live environment and the Xfce offline edition are shipping:Īnd it ships with these new features: x86_64: Gpg -verify Endeavouros_Cassini_Nova-03-2023_R2.iso.sig Uid Johannes Kamprad (joekamprad development key) This ISO is signed by: Johannes Kamprad pub rsa2048 ĨF43 FC37 4CD4 CEEA 19CE E323 E3D8 752A CDF5 95A1 (Do not forget to trust the key after validating it) To check the ISO file with gpg signature import our key and verify
Back to Blog
Black baby alive snackin sara8/2/2023 I mean she thinks its funny to hide in dark rooms and jump out yelling boo. My 1 year old has no fear so her reaction isn’t really an indicator. My 3 year old is afraid of literally everything and she was not frightened by Snackin’ Sara at all. I noticed many have said their child was scared by the toy (a 6 year old even?!) and that was absolutely not the case in our experience. I do usually read Amazon reviews before I finalise my reviews in case I have missed on details or had a different experience so I can test the product again. The juice box does not get filled with water or pretend juice, she simply “drinks” from the straw when it is placed in her mouth It’s nice and clean play which is great for younger kids. There is no mess at all inside the doll or in the diaper. When she is full you simply remove the diaper which is filled with the previously made food. She was trying at first to jam the food in the dolls mouth but that was something else that was easy to correct by simply demonstrating how to carefully put the food in the dolls mouth enough for the doll to eat the food. ![]() My 3 year old has had no issue with shaping the food to the right thickness after I showed her how to do it. The doll speaks in either English or French (in the USA she speaks Spanish instead of French), and she can say when she is hungry, sleepy or full. (This doll is meant for 3+ so this was definitely a parenting issue and not a toy issue.) There is a panel at the back of her head you can unscrew and that makes cleaning up this kind of mess super easy.īasically kids can use the shaping tools to make snacks to feed the Snackin’ Sara doll. She has made little to no mess, aside from the time my 1 year old smooshed the “food” into her mouth and really packed it in. She also comes with 2 diapers to catch the food she expels but using them is fairly optional. She comes with reusable doll food (play-doh), shaping tools, a plate and a pretend juice box. She is a cute little baby doll who loves to be fed snacks. That is what I love about Baby Alive Super Snacks Snackin’ Sara Doll. Some of the babies can eat and expel but since the girls are young, and messy in general, I don’t usually let them play that way. ![]() ![]() They do have a favourite baby who has her own cradle and gets tucked in to sleep, pushed around in a stroller and generally cared for. They have a collection of babies including a few Baby Alive dolls. Both my girls, 3 and 1, love dolls, and love babies.
Back to Blog
Each IP address identifies the device’s host network and the location of the device on the host network. IP address: An IP address is a unique number assigned to every device connected to a network that uses the Internet Protocol for communication. The following are some common terms to know when discussing computer networking: A VPN establishes an encrypted channel that keeps a user’s identity and access credentials, as well as any data transferred, inaccessible to hackers VPN (virtual private network): A VPN is a secure, point-to-point connection between two network end points (see ‘nodes’ below). CANs serve sites such as colleges, universities, and business campuses A CAN is larger than a LAN but smaller than a WAN. ![]() (For more information on how a SAN works with block storage, see Block Storage: A Complete Guide)ĬAN (campus area network): A CAN is also known as a corporate area network. SAN (storage area network): A SAN is a specialized network that provides access to block-level storage-shared network or cloud storage that, to the user, looks and works like a storage drive that’s physically attached to a computer. For example, if you have an iPhone and a Mac, it’s very likely you’ve set up a PAN that shares and syncs content-text messages, emails, photos, and more-across both devices PAN (personal area network): A PAN serves one person. Cities and government entities typically own and manage MANs MAN (metropolitan area network): MANs are typically larger than LANs but smaller than WANs. ![]() You will typically see collective or distributed ownership models for WAN management The internet is the largest WAN, connecting billions of computers worldwide. WAN (wide area network): As the name implies, a WAN connects computers over a wide area, such as from region to region or even continent to continent. WLAN (wireless local area network): A WLAN is just like a LAN but connections between devices on the network are made wirelessly Typically, LANs are privately owned and managed For example, a LAN may connect all the computers in an office building, school, or hospital. ![]() LAN (local area network): A LAN connects computers over a relatively short distance, allowing them to share data, files, and resources. Here are the most common and widely used computer network types: The internet, online search, email, audio and video sharing, online commerce, live-streaming, and social networks all exist because of computer networks.Īs networking needs evolved, so did the computer network types that serve those needs. You can further define a computer network by the protocols it uses to communicate, the physical arrangement of its components, how it controls traffic, and its purpose.Ĭomputer networks enable communication for every business, entertainment, and research purpose. The internet is the largest example of a WAN, connecting billions of computers worldwide. For example, a LAN (local area network) connects computers in a defined physical space, like an office building, whereas a WAN (wide area network) can connect computers across continents. Geographic location often defines a computer network. ![]() You build a computer network using hardware (e.g., routers, switches, access points, and cables) and software (e.g., operating systems or business applications). A computer network comprises two or more computers that are connected-either by cables (wired) or WiFi (wireless)-with the purpose of transmitting, exchanging, or sharing data and resources.
Back to Blog
Git sourcetree rename branch8/2/2023 ![]() branch and start developing a custom module within your branch. Replace the old parent branch with new parent branch. git source control system, you can easily clone either of these projects. This solution causes additional work to do. You need to ask someone in your team to check again your code and approve it. In case when you need to create a new branch, you need to create also new pull/merge request. Teams use pull/merge requests to the code review. ![]() In many companies, there is workflow how new functionality should go to master branch. This solution is OK, when you don’t have many commits, because for each commit you need to do git cherry-pick. We can create a new branch with parent master branch and use git cherry-pick command to move each commit from one branch to another. ![]() A local repository Let’s transition a local repository that isn’t pushed anywhere. Let’s look at two scenarios: changing a local repository, and changing a repository on GitHub. First is easy to understand, but a little bit time consuming. tools Git: how to rename master to main Watch on Renaming the default branch in Git from master to main is easy. For example, when a developer makes a commit, they can include the Jira Software issue key in the commit message: git commit -m 'PROJ-123 add a README file to the project. The problem which I described above, can be resolved in at least two ways. To link GitHub commits, branches, and pull requests to Jira issues, you need to include the Jira issue key in the commit message, branch name, or PR title. How can I handle it? Well, here is the time for git. What I should do in this situation? I need to merge my current branch before I will merge this other feature branch and I don’t want to add not needed commits to mater branch. I created it from some feature branch not from the master. I did some commits there, but after a while I noticed, that I created this new branch from the wrong parent branch.
Back to Blog
8x10 home office layout8/2/2023 ![]() You can also change rooms if you find that your current location isn't as effective as it could be. For example, you could put your desk up against your window at first, but if that doesn't meet your needs, you can move it somewhere else that does. At home, you can design your home office any way you'd like. You are not tied to a set layout like you are in a traditional office or communal workspace. One of the perks of laying out your home office is the ability to make it your own. ![]() Related: 5 Tips To Negotiate for a Cost of Living Adjustment 5. If you can, talk to your employer about your cost of living and how that can be reflected when planning your home office's layout. If this is not possible, try using a white noise machine or investing in noise-canceling headphones to block out any distracting noises while you work. If you live in an area where outside noises such as school-bound children and traffic are common, find an area that is furthest from these distractions. If you are next to high-traffic areas like the kitchen or playroom or are facing a busy road, make arrangements to separate yourself from distractions. Consider your office's locationīe conscious of where your office is located in your home when planning its layout. Related: Best Home Office Organization Ideas 4. You should also consider what you will need during your regular workday to stay productive, such as a chair with an appropriate height, a clock to keep time and lighting to help you focus on work without straining your eyes. For example, if you'll need to meet with people in person or over video chat, create a space for that. Keep in mind how you need your home office to work. If you need some inspiration for setting up your layout, ask friends and coworkers about their home offices to get a general idea of what works best. If you double your living room as an office instead, find ways to put home office supplies away when you're not using them so that your guests can feel more at home when they visit. If your home office doubles as another space, consider ways to partition the space or use furniture for multiple uses.įor example, if your bedroom is also your office, set the bed up in one half of the room, the workspace in the other and have a temporary divider between the two halves to truly separate the spaces. Whether you're building onto your home or using a dedicated room or area as an office, it's important to come up with a general idea of how you'll use each part of your space before you start laying it out. ![]() Have an idea in mind before setting up your layout Clean and clutter-free spaces can help improve mental health and relieve stress. Having a home office that's free of clutter creates a healthier environment to work in and helps you become more efficient and productive. To make sure that everything in the room has a home, take advantage of shelving and cabinets in your office or invest in a desk with shelves and storage. When creating a layout for your home office, create a space that hides clutter and promotes cleanliness. Use pieces you do have in different ways to make up for anything you're missing, such as transforming an unused dresser into storage and a temporary desk. This allows you to save up for bigger purchases and decorative pieces, such as office chairs and plants. Then, decide what items you need to complete your layout. Assess your current setup to see if it is practical and fits your needs. Start with what you have before making new purchases. Related: How To Get Motivated at Work Tips to help you design your home officeįollow these seven tips to create your perfect home office layout: 1. When designing your home office, keep in mind that space should: Related: The Pros and Cons of Working From Home What to look for in your home office layoutĬhoose a home office layout that creates a productive work environment and works best for your needs. In this article, we share tips for the layout of your home office. The space you work in can set the tone for the work you do, and if your home office is laid out in an organized manner, your work ethic may reflect this. If you need to set up a home office for regular or occasional use, it's important to plan a functional and enjoyable layout.
Back to Blog
Olly slim protein powder8/2/2023 ![]() Imported from USA (Sizes & Specifications are based on the USA Market).You'll love OLLY products if you've used products from Shakeology, Garden of Life, Orgain, TrueFit, PlantFusion, KetoLogic, Organifi and ALOHA. OLLY IS DIFFERENT: Try our plant based protein powders and discover for yourself how we're different.Taking nutritional supplements shouldn't be a chore, which is why ours are just as effective as they are fun. WE'RE OLLY: We've made it our personal mission to make nutrition easy to understand, so you can pursue good health without compromise. We use high quality, non-GMO pea protein and flaxseed in our vegan friendly powders. Plant-based protein + slimming boost from: blood orange only 5 g of sugar. ![]() PLANT BASED PROTEIN POWDER: Drink to your good health when you enjoy a protein shake or smoothie made from OLLY protein powders.Sip some protein in your meal, don't skip it. ![]()
Back to Blog
Actually funny minion memes8/2/2023 ![]() “Get those reports for me right meow.” 14) “When you show somebody a picture on your phone and they start scrolling.” 13) While you’re at it, share these funny memes on Facebook right meow! “Why couldn’t the bike stand on its own? Because it’s two-tired.” 12) Didn’t write ‘thank you’ on her check.” 10) 11) Give it up for funny memes! “One of my bar guests was rude, obnoxious, and kept complaining about her ‘weak drinks’. ![]() “Babe, are you mad? No! Are you sure baby? Yes! Can you smile for me?” 9) “This albino squirrel comes to our door and rubs its nipples and just stares at us.” 7) “How to Even for Dummies.” 6) Maybe he stares at the funny memes on your computer. “Ha, ha!! Now your pee stinks!” 5) Funny memes for dummies. “May your turkey be moist and may no one use that word to describe it.” 4) Do you know what doesn’t stink? Funny memes. “There’s a 50% chance these are full of buttons.” 3) Moist funny memes? Anyone? Anyone? “How you look when you wake up & the charger wasn’t plugged in.” 2) There’s also a 50% chance you’ll enjoy the following funny memes! Here is my collection of 101 funny memes to help bring a smile to your day. We did the heavy lifting for you and scoured the interweb for the funniest memes ever. While you can say that all memes are technically funny memes, only the best memes can truly become classic funny memes. While there is some debate about the first meme, internet memes vary from everything from funny memes to memes about pop culture, the day of the week, and everything in between. While the term ‘internet meme’ was first coined by Mike Godwin in a June 1993 issue of Wired.
Back to Blog
![]() ![]() majority of tasks we complete includes creating custom-written Unit 7 Polynomials And Dagmare of. The Red Prince is an Origin or a Companion in Divinity Original Sin 2. Statue of Illusions Answers in Divinity Original Sin 2. If you can overlook this, hes probably the most interesting of them all. Divinity: Original Sin 2 - Lunar Temple entrance puzzle - YouTube 0:00 / 1:11. Ifan, the most hollywood typical story of them all he wont surprise you with absolutely anything, hes the edgy human that has a troubled past and now is a killer for hire, BUT his story fits insanely well with the main story of the game, i tend to allways bring ifan into the party, or play as him, even better.įane, unique, rich story, by far the best story, but immersion is going to be obliterated by the lack of unique dialogues in most scenarios, hes supposed to be an ancient being, still he speaks like if hes another ifan. My favorite story has been Sebille’s, with Lohse’s in second. I’m looking forward to playing through again at some point with Red Prince and Beast. I went with the four characters I found most interesting at the start Ifan, Sebille, Lohse, and Fane. Sebille, typical rogue looking for revenge type of thing, by far the worst story wise since they changed it midgame and it looks like shes 2 characters in 1, they never fixed that, still its the only elf and her story really fits a rogue, it might also be what you want. I haven’t seen much of The Red Prince’s story because I never have him in my party. ![]() Red Prince, the story itself is quite ♥♥♥♥♥♥ for me, but the character is also unique and can be interesting if you can witstand his annoying voice. As with Divinity: Original Sin, players can play solo or with up to three others in. Lohse, quite unique and interesting storyīeast, standard dwarf stereotype, no flavour, but it might be just what you want, i like him. How many companions can you have in multiplayer Divinity: Original Sin 2. Companions in Divinity: Original Sin 2 play a very important role as they add variety to the gameplay and help out during battles. Its personal preference, in my eyes its like this: updated Divinity can be a tough game, so with that in mind, we put together a list of characters and classes that are so strong, it will make any enemy a joke.
Back to Blog
Clear gelatin with fruit8/2/2023 ![]() Let the syrup cool down to 140F and add the gelatin. To purchase gelatin art supplies visit our online store here. Then bring to a boil the water and the sugar to make a syrup. Dry surface will crack and tear when cut with sharp tools. When gelatin has fully set, close the containers with matching lids or cover them with foil to prevent them from drying. Leave in the fridge for several hours or overnight. Pour into desired containers and remove all air bubbles from the surface. It is a protein that has been extracted from certain animal bones and skins. Let it cool in the pan for 1-2 hours at room temperature until it becomes clear and the foam disappears from the surface. ![]() Stir until it dissolves completely and there are no clumps left in the liquid (Do not let the water reach the boiling point!) Remove from heat when you notice vapor appearing above the water. Heat 3 cups of water, 2 cups of sugar and 1 teaspoon of citric acid in a saucepan, stirring occasionally to dissolve all ingredients. Simply add water to your gelatin to thicken it, and while it’s doing its thing, heat your heavy cream, sugar, and vanilla bean (or extract) in a saucepan. Mix 3 tablespoons of gelatin powder with 1 cup of cold water and let it soak (bloom) for 10-15 min until all the water has been absorbed. ![]() You can also add lemon juice if you do not wish to use artificial flavors but be careful about using natural citrus oils as they don’t dissolve in water and remain as greasy spots on the surface. Since the gelatin base is already sweet and a bit sour from the citric acid, citrus and fruit flavors tend to give the best results. ( The amount of food flavoring you add will depend on the kind of flavoring you use. It is sweet and creamy and you can make it with whatever colors and flavors you prefer. Red ruby milk pudding– A famous Thai restaurant dessert made in a low-fat version and served as a pudding.Preparing clear gelatin for gelatin art is simple and easy, but remember, it takes a long time for gelatin to set, so plan ahead and prepare it a day in advance. What is Mosaic Gelatin (Gelatina de Mosaico) Mosaic gelatin really is nothing more than multiple colors of prepared gelatin, which is then mixed with a sweet, creamy gelatin made with sweetened condensed milk and unflavored gelatin. Milo jelly-A kids’ friendly jelly recipe made using simple ingredients like milo and agar-agar. White chocolate mango cups– Mango dessert recipe placed inside homemade white chocolate cups. Otherwise use white sugar or raw powdered sugar. So we start the recipe by sprinkling three teaspoons of the unflavored gelatin over one third cup (80 ml) of cold water and then leave it, untouched, for about. In a mixing bowl, combine 1 pouch Knox Unflavoured Gelatine with 2 tablespoons (25mL) of sugar. Add 1/4 cup (50mL) boiling water, stir constantly until granules are completely dissolved. This is like my childhood, only better,' says reviewer Lorraine. In mixing bowl, sprinkle 1 pouch Knox Unflavoured Gelatine over 1/4 cup (50mL) cold liquid. The result is truly heavenly 'My mother made this for us, when I was young, in the 50s and 60s. ![]() You can avoid adding sugar if the fruits and lychee juice are sweet enough. 01 of 16 Heavenly Raspberry Dessert View Recipe Jody Jell-O is blended with chunks of angel food cake, raspberries, and whipped cream, then set in a Bundt pan or mold of your choice. I am using lychee juice as a base to get the clear, see-through jelly. I am using some of the tropical fruits here to boost up the nutritious value and they include kiwi, mango, jackfruit, dragon fruit and pomegranate. They don’t only taste great, they also have enormous health benefits and should be considered an essential part of a healthy diet if living in these tropical regions. Tropical fruits are a variety of brightly coloured and nutritious fruits. I used a scissor to chop them into small pieces and I used a spice grinder to make the agar into tiny pieces to make the process easier. Video can’t be loaded because JavaScript is disabled: How to make clear agar-agar jelly fruit cake | TROPICAL FRUIT | gelatin free () Agar-agar jelly fruit cake ingredientsĪgar-agar is a vegetarian substance used to make jellies. |